Plasma cell myeloma with anaplastic transformation
نویسندگان
چکیده
منابع مشابه
Morphological Transformation of Myeloma Cells into Multilobated Plasma Cell Nuclei within 7 Days in a Case of Secondary Plasma Cell Leukemia That Finally Transformed as Anaplastic Myeloma
A 48-year-old man was diagnosed with multiple myeloma (IgG-k) and was treated with high-dose dexamethasone as an induction therapy followed by thalidomide-based regimens. Approximately 22 months after the initial diagnosis, the patient developed secondary plasma cell leukemia (PCL) with a white blood cell (WBC) count of 20.2 × 109/L including 79.5% plasma cells. A G-banding chromosomal analysis...
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Myeloma is the most common neoplasm of bone.The majority is diagnosed with a bone marrow aspirate, rather than a bone biopsy. Most patients have disseminated disease, associated with a poor prognosis. Some have solitary myeloma with a more favourable clinical course but eventually, most become multifocal. A small percentage of patients have sclerotic bone lesions, which may be associated with p...
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ژورنال
عنوان ژورنال: Blood
سال: 2016
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2016-08-731844